Protocol for FET #3

My next FET will vary from my last one in a number of ways. To prep, I am going to do an endometrial scratch and a long course of antibiotics (to treat any possible infection). My last cycle, I had a combo saline sonogram/mini scratch. While my doctor doesn’t put much stock in the scratch, he is willing to do it as it cannot hurt our outcome.     We are also going to follow my natural cycle, with supplementation of estrace and progesterone, only as needed.  There will be 0 medicated suppression.  The immune protocol will remain the same.

Let’s be honest, things aren’t very positive here right now.   We’ve been actively pursing infertility treatments since March 2011 and we have 0 living children.   Short of using a gestational carrier, there isn’t much more we can do to make this work.

Supplements (daily):
Vitamin E (400-600iu), Vitamin D (2000iu), Calcium (500mg twice a day), and Fish Oil (1000mg)

FET Medications
Prenatals
Estrace Pills (Oral)
Progesterone in Ethyl Oleate (100ml / 2m l)
Doxycycline (for 2 weeks)

Immune Medications
Metanx
Baby aspirin
Prednisone 20mg
Lovenox (30mg 2x a day until first ANTI-Xa)
Intralipids

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Drug Interactions and Supplement Absorption Crazy

Someone in my Facebook Reproductive Immunology Support group pointed out that I was taking my calcium at the completely wrong time.   In fact, she said,  I should not be taking it with iron (i.e. my multi-vitamin), but should be taking it with my vitamin D.

This sent my crazy brain into overdrive.  Shouldn’t I be taking my medications in a way that maximizes each and minimizes the less than ideal interactions?    OF COURSE I SHOULD.  I am still trying to decide if the subsequent hours of googling/reserach are the mark of intelligence or excessivism, but maybe I will just settle on a little bit of both?  Here’s a peek into the sticky note from my desktop:

no vitamin E with fish oil
no vitamin E with aspirin
no vitamin E with prenatal
no vitamin E with metanx
no vitamin E with Lovenox
no doxy with prenatal
no doxy with calcium
no doxy with aspirin
no doxy with any vitamins
no doxy with fish oil
no metanx with aspirin
no metanx with d
no metanx with fish oil
no metanx with vitamin E
etc…

I am a night owl by nature, so that is a bit of a roadblock for me in terms of spacing medications properly/psychotically.   Also, I will be relieved when the Doxycycline is out of the lineup, so I can move things around a bit.     Either way, I now have a medicine schedule that has me injecting or swallowing a pill nonstop.  Fan-tastic.   Behold my crazy:

10AM – Lovenox, Doxycycline
12PM – Prednisone
2PM – Estrace, Vitamin D, Calcium
4PM – Vitamin E
6PM – Metanx
8PM – Calcium
9PM – EV2, Progesterone, Prenatal
10PM – Lovenox
11PM – Doxycycline
12AM – Probiotic, Baby Asprin, Fish Oil

FET Audience

Since we have 4 frozen normal embryos, we are leaning towards attempting a frozen embryo transfer soon.  I don’t have much confidence that I can carry a baby to full-term, so I suspect the FET process is something I will not highlight online (at this blog, or on the various forums where I participate) at all.     It is very painful to lose a baby and I believe that hurt is amplified after IVF and the transfer of a PGS normal embryo.

I know this blog is a resource for so many women looking for answers, so please try to understand It was painfully hard for me lose my baby in front of a virtual audience in 2012. I will however, list the proposed immune protocol from my doctors when it is finalized.

Which Way

I’d like to say things are getting better and staying better but it seems that returning to infertility treatments has halted and also reversed any healing I did after my miscarriage.

I hate hate hate where I am right now and I’m angry that I cannot seem to snap out of it. Women have miscarriages all the time, it’s not like I’m special or anything. I wish I knew how to just suck it up and move on. On one hand I remind myself that I only lost the pregnancy a few months ago but on the other hand I feel like I should of made more progress? I should be feeling better? I don’t know. It’s just, we put so much emotional, physical and financial effort into that baby we lost: 3 IVFs, a polyp removal, CCS testing, 1000’s of injections (FU Lovenox), the bulk of our savings, etc and now I just feel empty. I have always been a strong person and I feel so very defeated.

Yesterday I cancelled on my RE literally 1 hour before I was scheduled to have a procedure. Instead, I stayed in bed and cried for a few hours. My husband then called to see how the procedure went and was shocked when he heard I didn’t go. I always go. I finally dragged myself out of bed, worked a few hours and then cut out early for a manicure and pedicure. I am trying, but some days the sadness is just overwhelming.

Perhaps it isn’t just the miscarriage, but that I am so worn down after almost 2 years of failed infertility treatments? Why continue when we always get bad news? There are just so many obstacles against us. I don’t know how we will overcome my husbands sperm DNA fragmentation and I don’t know how to overcome the HLA match issues. Especially as there is now some concern about using Neupogen due to my blood clotting issues. While we are fine using a gestational carrier it is a huge expense for us on top of 2 years of expensive infertility treatments.

I’ll admit it, I bought Powerball tickets yesterday. Unlimited funds would really help us reach the goal of 1 baby. We won $7.

Just a note to those of you who sent me an email, txt, or left a message after my last post. Thank you for checking in. Thank you for taking 1 minute out of your day to say hello, commiserate or just support. It made me feel less alone.