Protocol for FET #3

My next FET will vary from my last one in a number of ways. To prep, I am going to do an endometrial scratch and a long course of antibiotics (to treat any possible infection). My last cycle, I had a combo saline sonogram/mini scratch. While my doctor doesn’t put much stock in the scratch, he is willing to do it as it cannot hurt our outcome.     We are also going to follow my natural cycle, with supplementation of estrace and progesterone, only as needed.  There will be 0 medicated suppression.  The immune protocol will remain the same.

Let’s be honest, things aren’t very positive here right now.   We’ve been actively pursing infertility treatments since March 2011 and we have 0 living children.   Short of using a gestational carrier, there isn’t much more we can do to make this work.

Supplements (daily):
Vitamin E (400-600iu), Vitamin D (2000iu), Calcium (500mg twice a day), and Fish Oil (1000mg)

FET Medications
Prenatals
Estrace Pills (Oral)
Progesterone in Ethyl Oleate (100ml / 2m l)
Doxycycline (for 2 weeks)

Immune Medications
Metanx
Baby aspirin
Prednisone 20mg
Lovenox (30mg 2x a day until first ANTI-Xa)
Intralipids

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Drug Interactions and Supplement Absorption Crazy

Someone in my Facebook Reproductive Immunology Support group pointed out that I was taking my calcium at the completely wrong time.   In fact, she said,  I should not be taking it with iron (i.e. my multi-vitamin), but should be taking it with my vitamin D.

This sent my crazy brain into overdrive.  Shouldn’t I be taking my medications in a way that maximizes each and minimizes the less than ideal interactions?    OF COURSE I SHOULD.  I am still trying to decide if the subsequent hours of googling/reserach are the mark of intelligence or excessivism, but maybe I will just settle on a little bit of both?  Here’s a peek into the sticky note from my desktop:

no vitamin E with fish oil
no vitamin E with aspirin
no vitamin E with prenatal
no vitamin E with metanx
no vitamin E with Lovenox
no doxy with prenatal
no doxy with calcium
no doxy with aspirin
no doxy with any vitamins
no doxy with fish oil
no metanx with aspirin
no metanx with d
no metanx with fish oil
no metanx with vitamin E
etc…

I am a night owl by nature, so that is a bit of a roadblock for me in terms of spacing medications properly/psychotically.   Also, I will be relieved when the Doxycycline is out of the lineup, so I can move things around a bit.     Either way, I now have a medicine schedule that has me injecting or swallowing a pill nonstop.  Fan-tastic.   Behold my crazy:

10AM – Lovenox, Doxycycline
12PM – Prednisone
2PM – Estrace, Vitamin D, Calcium
4PM – Vitamin E
6PM – Metanx
8PM – Calcium
9PM – EV2, Progesterone, Prenatal
10PM – Lovenox
11PM – Doxycycline
12AM – Probiotic, Baby Asprin, Fish Oil

Proposed Immune Protocol for FET

Supplements (daily):
Vitamin E (400-600iu), Vitamin D (2000iu), Calcium (500mg twice a day), Fish Oil (1000mg), and Probiotics

FET Medications
Prenatals
Lupron 10 units
DelEstrogen Injections
Estrace Pills
Progesterone in Ethyl Oleate (100ml / 2m l)
Doxycycline

Immune Medications
Metanx
Baby aspirin
Prednisone 20-30mg
Lovenox (30mg 2x a day until first ANTI-Xa)
Intralipids

FET Audience

Since we have 4 frozen normal embryos, we are leaning towards attempting a frozen embryo transfer soon.  I don’t have much confidence that I can carry a baby to full-term, so I suspect the FET process is something I will not highlight online (at this blog, or on the various forums where I participate) at all.     It is very painful to lose a baby and I believe that hurt is amplified after IVF and the transfer of a PGS normal embryo.

I know this blog is a resource for so many women looking for answers, so please try to understand It was painfully hard for me lose my baby in front of a virtual audience in 2012. I will however, list the proposed immune protocol from my doctors when it is finalized.

Well Hello, Lupron

6 IVFs since 2011 and I’ve never tried Lupron.  Times are a changin’ as it’s now on deck for IVF #7.  As is a completely new protocol.  And a new doctor.  At a new clinic.

The worst that can happen is we get 0 blasts again, but let’s be honest here, we are very experienced in cycles that result in 0 blasts.

After reviewing our history (it’s a novel really) and sitting with our new doctor, he didn’t pull any punches.  He said we have issues from all sides of the infertility spectrum and we cannot realistically expect high blast counts.

This was not news to us, but I am glad he didn’t try to sell us the world.

He also said he’s seen many couples like us, and he was genuinely surprised we didn’t look more defeated.    I told him if he had seen me after my miscarriage, he would of felt differently,

Prior to IVF #7 in March, we are going to take a quick, cheap vacation.    I am exhausted.